8-Cl-Ado and 8-NH2-Ado synergize with venetoclax to target the methionine-MAT2A-SAM axis in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2024 at "Leukemia"
DOI: 10.1038/s41375-024-02222-w
Abstract: Targeting the metabolic dependencies of acute myeloid leukemia (AML) cells is a promising therapeutical strategy. In particular, the cysteine and methionine metabolism pathway (C/M) is significantly altered in AML cells compared to healthy blood cells.… read more here.
Keywords: methionine; ado; sam axis; methionine mat2a ... See more keywords
Anxiolytic effects of vestibular stimulation: an update
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2023-0022
Abstract: Abstract The vestibular system inhibits both HPA and SAM axis and contributes to the management of anxiety. Both direct and indirect pathways exist in the inhibition of the HPA and SAM axis. In this review… read more here.
Keywords: vestibular stimulation; sam axis; hpa sam; effects vestibular ... See more keywords