Salt Dependence Conformational Stability of the Dimeric SAM Domain of MAPKKK Ste11 from Budding Yeast: A Native State H/D Exchange NMR Study".
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00522
Abstract: The sterile α motif, also called the SAM domain, is known to form homo or heterocomplexes that modulate diverse biological functions through regulation of specific protein-protein interactions. The MAPK pathway of budding yeast Saccharomyces cerevisiae… read more here.
Keywords: ste11; sam; exchange; sam domain ... See more keywords
The SAM domain of mouse SAMHD1 is critical for its activation and regulation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02783-8
Abstract: Human SAMHD1 (hSAMHD1) is a retroviral restriction factor that blocks HIV-1 infection by depleting the cellular nucleotides required for viral reverse transcription. SAMHD1 is allosterically activated by nucleotides that induce assembly of the active tetramer.… read more here.
Keywords: mouse samhd1; sam domain; samhd1; domain ... See more keywords
Disruption of polyhomeotic polymerization decreases nucleosome occupancy and alters genome accessibility
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202201768
Abstract: Disruption of SAM domain–mediated polymerization of Polycomb Group protein polyhomeotic decreases nucleosome occupancy in Drosophila S2 cells. Chromatin attains its three-dimensional (3D) conformation by establishing contacts between different noncontiguous regions. Sterile Alpha Motif (SAM)–mediated polymerization… read more here.
Keywords: nucleosome occupancy; sam domain; decreases nucleosome; chromatin ... See more keywords
Linker-Mediated Inactivation of the SAM-II Domain in the Tandem SAM-II/SAM-V Riboswitch
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252011288
Abstract: Tandem SAM-II/SAM-V riboswitch belongs to a class of riboswitches found in the marine bacterium ‘Candidatus Pelagibacter ubique’. Previous studies have demonstrated that these riboswitches have the potential for digital modulation of gene expression at both… read more here.
Keywords: tandem sam; sam domain; sam; linker ... See more keywords