Salt Dependence Conformational Stability of the Dimeric SAM Domain of MAPKKK Ste11 from Budding Yeast: A Native State H/D Exchange NMR Study".
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00522
Abstract: The sterile α motif, also called the SAM domain, is known to form homo or heterocomplexes that modulate diverse biological functions through regulation of specific protein-protein interactions. The MAPK pathway of budding yeast Saccharomyces cerevisiae… read more here.
Keywords: ste11; sam; exchange; sam domain ... See more keywords
The SAM domain of mouse SAMHD1 is critical for its activation and regulation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02783-8
Abstract: Human SAMHD1 (hSAMHD1) is a retroviral restriction factor that blocks HIV-1 infection by depleting the cellular nucleotides required for viral reverse transcription. SAMHD1 is allosterically activated by nucleotides that induce assembly of the active tetramer.… read more here.
Keywords: mouse samhd1; sam domain; samhd1; domain ... See more keywords
Disruption of polyhomeotic polymerization decreases nucleosome occupancy and alters genome accessibility
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202201768
Abstract: Disruption of SAM domain–mediated polymerization of Polycomb Group protein polyhomeotic decreases nucleosome occupancy in Drosophila S2 cells. Chromatin attains its three-dimensional (3D) conformation by establishing contacts between different noncontiguous regions. Sterile Alpha Motif (SAM)–mediated polymerization… read more here.
Keywords: nucleosome occupancy; sam domain; decreases nucleosome; chromatin ... See more keywords