Radical SAM enzymes: Nature's choice for radical reactions
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14519
Abstract: Enzymes that use a [4Fe‐4S]1+ cluster plus S‐adenosyl‐l‐methionine (SAM) to initiate radical reactions (radical SAM) form the largest enzyme superfamily, with over half a million members across the tree of life. This review summarizes recent… read more here.
Keywords: radical sam; reactions radical; sam; radical reactions ... See more keywords
Making and breaking carbon-carbon bonds in class C radical SAM methyltransferases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2021.111636
Abstract: Radical S-adenosylmethionine (SAM) enzymes utilize a [4Fe-4S]1+ cluster and S-(5'-adenosyl)-L-methionine, (SAM), to generate a highly reactive radical and catalyze what is arguably the most diverse set of chemical reactions for any known enzyme family. At… read more here.
Keywords: sam enzymes; carbon; radical sam; class radical ... See more keywords