SAMHD1 and the innate immune response to cytosolic DNA during DNA replication.
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DOI: 10.1016/j.coi.2018.09.017
Abstract: Cytosolic DNA of endogenous or exogenous origin is sensed by the cGAS-STING pathway to activate innate immune responses. Besides microbial DNA, this pathway detects self-DNA in the cytoplasm of damaged or abnormal cells and plays… read more here.
Keywords: dna; cytosolic dna; samhd1 innate; innate immune ... See more keywords