LAUSR

SAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining

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1 Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab051

Abstract: Abstract Aberrant end joining of DNA double strand breaks leads to chromosomal rearrangements and to insertion of nuclear or mitochondrial DNA into breakpoints, which is commonly observed in cancer cells and constitutes a major threat… read more here.

Keywords: end joining; end; samhd1 restrains; dna end ... See more keywords