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Published in 2019 at "British Journal of Haematology"
DOI: 10.1111/bjh.15819
Abstract: Myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN) and chronic myelomonocytic leukaemia (CMML) can progress to secondary acute myeloid leukaemia (sAML). We compared the outcome of 4214 sAML patients who received allogeneic haematopoietic stem cell transplantation (allo‐HSCT)…
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Keywords:
stem cell;
leukaemia;
saml;
disease ... See more keywords
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-061699
Abstract: Objectives Survivors of diffuse large B-cell lymphoma (DLBCL) are at an increased risk of developing second primary malignancies. However, the risk of secondary acute myeloid leukaemia (sAML) has not been previously described in detail, and…
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Keywords:
database;
seer database;
acute myeloid;
saml ... See more keywords
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Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-113779
Abstract: Background: Acute myeloid leukemia (AML) secondary to haematological neoplasia or other malignant diseases, defined as secondary AML (sAML), is thought to have an inferior prognosis as compared with de novo AML. However, when corrected for…
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Keywords:
cell;
analysis;
saml;
novo aml ... See more keywords
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-140212
Abstract: Transcriptional regulators (TFs) involved in cell-growth, differentiation and survival of AML stem/progenitor cells (LSCs) include RUNX1, PU.1, CEBPα, c-Myb and c-Myc. LSD1 (KDM1A) is an FAD-dependent amine-oxidase that demethylates mono and dimethyl histone H3 lysine…
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Keywords:
research;
honoraria research;
saml;
differentiation ... See more keywords