Expression of neurotransmitters, vasculogenesis markers and myosin heavy chain isoforms in the masseter muscle of senescence-accelerated mouse prone 8 mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13449
Abstract: BACKGROUND Learning and memory deficits and pathologic changes in the hippocampus caused by toothlessness and soft diet feeding are related to reduced masseter muscle (MM) function. OBJECTIVE Myosin heavy chain (MyHC) isoform expression in the… read more here.
Keywords: cgrp; senescence accelerated; expression; samr1 ... See more keywords
Auditory Threshold Variability in the SAMP8 Mouse Model of Age-Related Hearing Loss: Functional Loss and Phenotypic Change Precede Outer Hair Cell Loss
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2021.708190
Abstract: Age-related hearing loss (ARHL) is the most common sensory deficit in aging society, which is accompanied by increased speech discrimination difficulties in noisy environments, social isolation, and cognitive decline. The audiometric degree of ARHL is… read more here.
Keywords: age related; hair cell; age; samp8 ... See more keywords
Probing the relevance of the accelerated aging mouse line SAMP8 as a model for certain types of neuropsychiatric symptoms in dementia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2023.1054163
Abstract: Introduction People with dementia (PwD) often present with neuropsychiatric symptoms (NPS). NPS are of substantial burden to the patients, and current treatment options are unsatisfactory. Investigators searching for novel medications need animal models that present… read more here.
Keywords: accelerated aging; phenotype; aggression; neuropsychiatric symptoms ... See more keywords
Ferroptosis in a sarcopenia model of senescence accelerated mouse prone 8 (SAMP8)
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DOI: 10.7150/ijbs.53126
Abstract: As a systemic syndrome characterized by age-associated degenerative skeletal muscle atrophy, sarcopenia leads to a risk of adverse outcomes in the elderly. Age-related iron accumulation is found in the muscles of sarcopenia animal models and… read more here.
Keywords: sarcopenia; senescence accelerated; samp8; ferroptosis ... See more keywords