A review of blood sample handling and pre‐processing for metabolomics studies
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700086
Abstract: Metabolomics has been found to be applicable to a wide range of clinical studies, bringing a new era for improving clinical diagnostics, early disease detection, therapy prediction and treatment efficiency monitoring. A major challenge in… read more here.
Keywords: sample; handling pre; pre processing; sample handling ... See more keywords
A proposed sample handling of ovine cotyledon for proteomic studies.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113585
Abstract: Ovine trophoblast is a suitable material for placental studies. However, a universal protocol for handling ruminant cotyledon samples has still not been reported. Considering the villous structure of ovine cotyledon, we suggest procedures to prepare… read more here.
Keywords: proposed sample; handling ovine; cotyledon; ovine cotyledon ... See more keywords
Impact of clinical sample handling and processing on ultra-low level measurements of plasma cytokines.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.01.001
Abstract: OBJECTIVES In this study, we evaluated the impact of clinical sample handling and processing on IL-6, IL-10, IFNγ, and IL-2 measurements in plasma. DESIGN AND METHODS We collected whole blood samples and analyzed various pre-analytical… read more here.
Keywords: sample; handling processing; clinical sample; sample handling ... See more keywords
Sample handling of gastric tissue and O-glycan alterations in paired gastric cancer and non-tumorigenic tissues
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18299-6
Abstract: Sample collection, handling and storage are the most critical steps for ensuring the highest preservation of specimens. Pre-analytical variability can influence the results as protein signatures alter rapidly after tissue excision or during long-term storage.… read more here.
Keywords: handling gastric; gastric cancer; tissue; cancer ... See more keywords
How sample handling distorts telomere studies
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-08303-9
Abstract: Telomere length (TL) is investigated as a biomarker for aging and disease-susceptibility, but measurement using quantitative polymerase chain reaction (qPCR) faces challenges in accuracy and reproducibility. The potential impact of pre-analytical factors on TL measurements… read more here.
Keywords: processing; sample handling; distorts telomere; impact ... See more keywords
Sample handling, preparation and mounting for XPS and other surface analytical techniques
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Vacuum Science and Technology"
DOI: 10.1116/6.0000421
Abstract: Sample preparation and mounting are important aspects of x-ray photoelectron spectroscopy (XPS) analysis. New users do not know many techniques that are familiar to analysts with years of experience, and these observations and “tricks of… read more here.
Keywords: mounting xps; handling preparation; surface; sample handling ... See more keywords
Impact of sample handling protocols on soft tissue attenuation coefficient and morphology
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.30.10.106004
Abstract: Abstract. Significance The use of tissue attenuation coefficients as biomarkers for disease detection is rising. However, especially for ex vivo studies, sample handling methods can notably impact tissue optical attenuation properties, and these effects have… read more here.
Keywords: attenuation coefficient; tissue attenuation; handling methods; sample handling ... See more keywords
Alternative pre-analytic sample handling techniques for glucose measurement in the absence of fluoride tubes in low resource settings
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0264432
Abstract: Introduction Sodium fluoride (NaF) tubes are the recommended tubes for glucose measurements, but these are expensive, have limited number of uses, and are not always available in low resource settings. Alternative sample handling techniques are… read more here.
Keywords: low resource; resource settings; plasma; sample handling ... See more keywords