Overcoming Sample Matrix Effect in Quantitative Blood Metabolomics Using Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b02240
Abstract: Blood is widely used for discovery metabolomics to search for disease biomarkers. However, blood sample matrix can have a profound effect on metabolome analysis, which can impose an undesirable restriction on the type of blood… read more here.
Keywords: isotope labeling; sample matrix; effect; blood ... See more keywords
Detection of Autoantibodies in Saliva as New Avenue for the Diagnosis and Management of Autoimmune Patients
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12082026
Abstract: (1) Background: Autoimmune diseases are characterized by autoantibodies directed to a large number of antigenic targets and are measured using serum as sample matrix. Although serum is a very common specimen type, it comes with… read more here.
Keywords: autoantibodies saliva; detection autoantibodies; sample matrix; detection ... See more keywords