Focusing analytes from 50 μL into 500 pL: On-chip focusing from large sample volumes using isotachophoresis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10579-5
Abstract: The use of on-chip isotachophoresis assays for diagnostic applications is often limited by the small volumes of standard microfluidic channels. Overcoming this limitation is particularly important for detection of ‘discrete’ biological targets (such as bacteria)… read more here.
Keywords: sample; analytes 500; focusing analytes; sample volumes ... See more keywords
Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.72629
Abstract: Cryogenic electron microscopy has become an essential tool for structure determination of biological macromolecules. In practice, the difficulty to reliably prepare samples with uniform ice thickness still represents a barrier for routine high-resolution imaging and… read more here.
Keywords: structure; sample volumes; structure determination; picoliter sample ... See more keywords