Articles with "sampling alternative" as a keyword



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Sampling alternative conformational states of transporters and receptors with AlphaFold2

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Published in 2022 at "eLife"

DOI: 10.7554/elife.75751

Abstract: Equilibrium fluctuations and triggered conformational changes often underlie the functional cycles of membrane proteins. For example, transporters mediate the passage of molecules across cell membranes by alternating between inward- and outward-facing states, while receptors undergo… read more here.

Keywords: states transporters; conformational states; transporters receptors; sampling alternative ... See more keywords