Effect of Different Sampling Schedules on Results of Bioavailability and Bioequivalence Studies: Evaluation by Means of Monte Carlo Simulations.
Sign Up to like & getrecommendations! Published in 2017 at "Drug research"
DOI: 10.1055/s-0043-105797
Abstract: Bioavailability and bioequivalence study is one of the most frequently performed investigations in clinical trials. Bioequivalence testing is based on the assumption that 2 drug products will be therapeutically equivalent when they are equivalent in… read more here.
Keywords: bioequivalence; bioavailability; monte carlo; bioequivalence studies ... See more keywords
Simulation-Based Optimization of Sampling Schedules for Model-Informed Precision Dosing of Once-Daily and 4-Times-Daily Busulfan in Pediatric Patients
Sign Up to like & getrecommendations! Published in 2024 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000001217
Abstract: Supplemental Digital Content is Available in the Text. Background: Therapeutic drug monitoring (TDM) is crucial in optimizing the outcomes of hematopoietic stem cell transplantation by guiding busulfan (Bu) dosing. Limited sampling strategies show promise for… read more here.
Keywords: precision; pediatric patients; sampling schedules; model ... See more keywords