Involvement of Reactive Metabolites of Diclofenac in Cytotoxicity in Sandwich-Cultured Rat Hepatocytes
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DOI: 10.1177/1091581817700584
Abstract: Background and Objectives: Diclofenac (DIC) is metabolized to reactive metabolites such as diclofenac acyl-β-d-glucuronide (DIC-AG). It is possible that such reactive metabolites could cause tissue damage by formation of covalent protein adducts and other modification… read more here.
Keywords: covalent protein; dic dic; metabolites diclofenac; sandwich cultured ... See more keywords