Sanguinarine has anthelmintic activity against the enteral and parenteral phases of Trichinella infection in experimentally infected mice.
Sign Up to like & getrecommendations! Published in 2019 at "Acta tropica"
DOI: 10.1016/j.actatropica.2019.105226
Abstract: Trichinellosis is a zoonotic parasitic disease caused by Trichinella spiralis, and it is also a widely prevalent foodborne parasitic disease. At present, albendazole and benzimidazole are the most commonly used therapeutic drugs for the clinical… read more here.
Keywords: sanguinarine; sanguinarine anthelmintic; treated sanguinarine; mice ... See more keywords
Sanguinarine caused larval lethality and growth inhibition by suppressing energy metabolism in silkworms, Bombyx mori.
Sign Up to like & getrecommendations! Published in 2019 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2019.08.004
Abstract: Sanguinarine (Sang) is a natural alkaloid and distributed in several plants of Papaveraceae. The antitumor, antioxidant, antimicrobial and anti-inflammatory effects of Sang were extensively reported, but its speciality and mechanism against Lepidoptera insects were still… read more here.
Keywords: sanguinarine; energy metabolism; silkworms bombyx; energy ... See more keywords
Sanguinarine synergistically potentiates aminoglycoside‐mediated bacterial killing
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14017
Abstract: Aminoglycosides are one of the oldest classes of antimicrobials that are being used in current clinical practice, especially on multi‐drug resistant Gram‐negative pathogenic bacteria. However, the serious side effects at high dosage such as ototoxicity,… read more here.
Keywords: sanguinarine synergistically; mediated bacterial; potentiates aminoglycoside; synergistically potentiates ... See more keywords
pH-sensitive liposomes with benzophenanthridine alkaloid sanguinarine and their cytotoxic activity
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanotechnology"
DOI: 10.1504/ijnt.2021.118158
Abstract: The plant alkaloid sanguinarine has antitumour, antiangiogenic, antimicrobial and antiviral activity. However, the maximum manifestation of the therapeutic potential of sanguinarine is hindered by ... read more here.
Keywords: liposomes benzophenanthridine; alkaloid sanguinarine; benzophenanthridine alkaloid; activity ... See more keywords
Toxicological Effects of Berberine and Sanguinarine
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2018.00021
Abstract: Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced… read more here.
Keywords: berberine sanguinarine; toxicological effects; effects berberine; sanguinarine ... See more keywords
Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00136
Abstract: For decades, natural products represented a significant source of diverse and unique bioactive lead compounds in drug discovery field. In Clinical oncology, complete tumors remission is hampered by the development of drug-resistance. Therefore, development of… read more here.
Keywords: drug resistance; sanguinarine; drug; resistance ... See more keywords
Cytotoxic and Proapoptotic Activity of Sanguinarine, Berberine, and Extracts of Chelidonium majus L. and Berberis thunbergii DC. toward Hematopoietic Cancer Cell Lines
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DOI: 10.3390/toxins11090485
Abstract: Isoquinoline alkaloids belong to the toxic secondary metabolites occurring in plants of many families. The high biological activity makes these compounds promising agents for use in medicine, particularly as anticancer drugs. The aim of our… read more here.
Keywords: cell lines; sanguinarine; chelidonium majus; cell ... See more keywords
Sanguinarine induces apoptosis of human lens epithelial cells by increasing reactive oxygen species via the MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2019.10087
Abstract: Posterior capsular opacification (PCO) remains a major complication of cataract surgery and is the most common reason for loss of vision. PCO is primarily associated with uncontrolled proliferation of residual human lens epithelial cells (HLEs).… read more here.
Keywords: reactive oxygen; epithelial cells; lens epithelial; oxygen species ... See more keywords