517: EFFECT OF SANGUINATE ON CPB FUNCTION USING A BOVINE WHOLE BLOOD MODEL OF NORMOVOLEMIC HEMODILUTION
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000551269.48843.c2
Abstract: Learning Objectives: Cardiac surgery using cardiopulmonary bypass (CPB) carries a high risk of bleeding and need for perioperative blood transfusion. Blood transfusion is an expensive, resource-intensive intervention that is associated with increased rates of ICU… read more here.
Keywords: normovolemic hemodilution; sanguinate; hemodilution; cpb ... See more keywords
Effect of early Sanguinate (PEGylated carboxyhemoglobin bovine) infusion on cerebral blood flow to the ischemic core in experimental middle cerebral artery occlusion
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DOI: 10.1136/neurintsurg-2021-018239
Abstract: Background Sanguinate, a bovine PEGylated carboxyhemoglobin-based oxygen carrier with vasodilatory, oncotic and anti-inflammatory properties designed to release oxygen in hypoxic tissue, was tested to determine if it improves infarct volume, collateral recruitment and blood flow… read more here.
Keywords: ischemic core; blood flow; flow ischemic; pegylated carboxyhemoglobin ... See more keywords