Santalol Isomers Inhibit Transthyretin Amyloidogenesis and Associated Pathologies in Caenorhabditis elegans
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DOI: 10.3389/fphar.2022.924862
Abstract: Transthyretin (TTR) is a homotetrameric protein found in human serum and is implicated in fatal inherited amyloidoses. Destabilization of native TTR confirmation resulting from mutation, environmental changes, and aging causes polymerization and amyloid fibril formation.… read more here.
Keywords: inhibit transthyretin; ttr; amyloidogenesis associated; isomers inhibit ... See more keywords