Promotion of osteogenesis by Sweroside via BMP2‐involved signaling in postmenopausal osteoporosis
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DOI: 10.1002/ptr.7336
Abstract: Phlomis umbrosa has been traditionally used for bone diseases in traditional Korean Medicine. Sweroside (SOS), marker compounds of P. umbrosa, has been known to promote osteoblast differentiation. In this study, ameliorative effects of SOS on… read more here.
Keywords: bone; sweroside; saos cells; sos ... See more keywords
Anti-proliferation and anti-metastatic effects of sevoflurane on human osteosarcoma U2OS and Saos-2 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2019.04.005
Abstract: Sevoflurane is a commonly used anesthetic in cancer surgery. However, little information is available about the effects of sevoflurane on the osteosarcoma cells. The present study explored the effects of sevoflurane on the proliferation, migration… read more here.
Keywords: proliferation migration; saos cells; proliferation; u2os saos ... See more keywords
Influences of anandamide on the composition and microanatomy of bone formed in vitro by osteoblast-like Saos-2 cells
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DOI: 10.1152/physiol.2025.40.s1.2072
Abstract: The objective of our study was to investigate the influence of an endocannabinoid, anandamide (AEA), on bone formation in vitro by cultured osteosarcoma Saos-2 cells (HTB-85). Osteogenesis requires differentiation of cells to mature osteoblasts, followed… read more here.
Keywords: saos cells; physiology; microanatomy; bone ... See more keywords
Src and ROCK Kinases Differentially Regulate Mineralization of Human Osteosarcoma Saos-2 Cells
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DOI: 10.3390/ijms20122872
Abstract: Osteoblasts initiate bone mineralization by releasing matrix vesicles (MVs) into the extracellular matrix (ECM). MVs promote the nucleation process of apatite formation from Ca2+ and Pi in their lumen and bud from the microvilli of… read more here.
Keywords: saos cells; mineralization; rock kinases; human osteosarcoma ... See more keywords
Combination Treatment with Liposomal Doxorubicin and Inductive Moderate Hyperthermia for Sarcoma Saos-2 Cells
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DOI: 10.3390/ph17010133
Abstract: Despite efforts in osteosarcoma (OS) research, the role of inductive moderate hyperthermia (IMH) in delivering and enhancing the antitumor effect of liposomal doxorubicin formulations (LDOX) remains unresolved. This study investigated the effect of a combination… read more here.
Keywords: treatment; combination treatment; saos cells; moderate hyperthermia ... See more keywords
Combination Treatment with Free Doxorubicin and Inductive Moderate Hyperthermia for Sarcoma Saos-2 Cells
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DOI: 10.3390/ph18060852
Abstract: Background: Osteosarcoma (OS) is the most common primary malignant bone tumor. Doxorubicin (DOX) is extensively used in OS chemotherapy, yet improving patient outcomes remains challenging. This study investigated the effect of free DOX combined with… read more here.
Keywords: treatment; saos cells; dox; moderate hyperthermia ... See more keywords
MicroRNA-1226-3p has a tumor-promoting role in osteosarcoma
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DOI: 10.3892/ol.2021.12735
Abstract: Osteosarcoma is a malignant bone tumor that commonly occurs in young individuals. It accounts for 10% of solid tumors in those who are 15–19 years old. MicroRNA (miRNA/miR) dysregulation serves a crucial role in the… read more here.
Keywords: mir 1226; microrna 1226; saos cells; osteosarcoma ... See more keywords