Sapap4 deficiency leads to postsynaptic defects and abnormal behaviors relevant to hyperkinetic neuropsychiatric disorder in mice.
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DOI: 10.1093/cercor/bhac123
Abstract: Postsynaptic proteins play critical roles in synaptic development, function, and plasticity. Dysfunction of postsynaptic proteins is strongly linked to neurodevelopmental and psychiatric disorders. SAP90/PSD95-associated protein 4 (SAPAP4; also known as DLGAP4) is a key component… read more here.
Keywords: sapap4; neuropsychiatric disorder; hyperkinetic neuropsychiatric; abnormal behaviors ... See more keywords