Total saponins of panax ginseng via the CX3CL1/CX3CR1 axis attenuates neuroinflammation and exerted antidepressant‐like effects in chronic unpredictable mild stress in rats
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DOI: 10.1002/ptr.7696
Abstract: Total saponins of Panax ginseng (TSPG) have antidepressant effects. However, the underlying antidepressant mechanism of TSPG remains not clear. This study aimed to predict the mechanism of TSPG by bioinformatics analysis and to verify it… read more here.
Keywords: total saponins; cx3cl1 cx3cr1; cx3cl1; saponins panax ... See more keywords
Steaming Changes the Composition of Saponins of Panax notoginseng (Burk.) F.H. Chen That Function in Treatment of Hyperlipidemia and Obesity.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c00746
Abstract: Saponins of Panax notoginseng (Burk.) F.H. Chen have been classified as a type of composition in functional foods for numerous diseases. However, its mild effects and other characteristics limited clinical applications in diseases. Inspired by… read more here.
Keywords: panax notoginseng; hyperlipidemia; composition; saponins panax ... See more keywords
Saponins from Panax japonicus alleviate adipose tissue fibrosis and metabolic dysfunction in high-fat-diet-induced obese mice
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DOI: 10.1080/1354750x.2022.2122566
Abstract: ABSTRACT Introduction Adipose tissue fibrosis is a typical feature of adipose tissue dysfunction in obese individuals, which is closely related to metabolic diseases. Objective To explore the effect and mechanism of Saponins from Panax japonicus… read more here.
Keywords: obese mice; adipose tissue; saponins panax; fibrosis ... See more keywords
AB0066 MECHANISMS OF TOTAL SAPONINS OF PANAX JAPONICUS MITIGATES COLLAGEN-INDUCED ARTHRITIS
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.3496
Abstract: Total saponins of Panax japonicus (TSPJ) are extracted from Panax japonicus (T.Nees) C.A.Mey and have achieved a good therapeutic effect in the treatment of rheumatoid arthritis (RA). Unfortunately, the mechanism of TSPJ acting on RA… read more here.
Keywords: histology; saponins panax; panax japonicus; arthritis ... See more keywords
Saponins from Panax japonicus attenuate age-related neuroinflammation via regulation of the mitogen-activated protein kinase and nuclear factor kappa B signaling pathways
Sign Up to like & getrecommendations! Published in 2017 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.219047
Abstract: Neuroinflammation is recognized as an important pathogenic factor for aging and related cognitive disorders. Mitogen-activated protein kinase and nuclear factor kappa B signaling pathways may mediate neuroinflammation. Saponins from Panax japonicus are the most abundant… read more here.
Keywords: kinase; saponins panax; japonicus; panax japonicus ... See more keywords