An LC–MS/MS method for simultaneous determination of nine steroidal saponins from Paris polyphylla var. in rat plasma and its application to pharmacokinetic study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.07.052
Abstract: HighlightsAn UPLC–MS/MS method to quantify 9 saponins from Paris polyphylla was developed and validated.The sensitive and robust method was successfully used in a pharmacokinetic study in SD rats.PK profiles of the 9 major components in… read more here.
Keywords: method; polyphylla; paris polyphylla; pharmacokinetic study ... See more keywords
Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00673
Abstract: Saponins are amphipathic glycosides found in traditional Chinese medicines. In the present study, we isolated a panel of saponins from Paris forrestii (Takht.) H. Li, a unique plant found in Tibet and Yunnan provinces, China.… read more here.
Keywords: mtor signaling; paris forrestii; tspf; mtor ... See more keywords