Human-transmissible sarbecovirus ‘Khosta-2’ similar to SARS-CoV-2: potential global threat?
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Medicine and Surgery"
DOI: 10.1097/ms9.0000000000000486
Abstract: Although hundreds of sarbecoviruses have been identified, mostly in Asian bats, but the majority do not infect human cells. Very recently, numerous sarbecoviruses are discovered in Russian horseshoe bats. The majority of these also do… read more here.
Keywords: sarbecovirus; human cells; microbiology; khosta ... See more keywords
The Glycan-Binding Trait of the Sarbecovirus Spike N-Terminal Domain Reveals an Evolutionary Footprint
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00958-22
Abstract: Spike N-terminal domains (S-NTD) of sarbecoviruses are highly diverse; however, their function remains largely understudied compared with the receptor-binding domains (RBD). Here, we show that sarbecovirus S-NTD can be phylogenetically clustered into five clades and… read more here.
Keywords: glycan binding; cell; sarbecovirus; spike terminal ... See more keywords
Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan
Sign Up to like & getrecommendations! Published in 2020 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2612.203386
Abstract: Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein… read more here.
Keywords: sarbecovirus; characterization bat; phylogenetically related; detection characterization ... See more keywords