Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies.
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DOI: 10.1002/adfm.202003237
Abstract: Tumor-derived extracellular vesicles (EVs) play essential roles in intercellular communication during tumor growth and metastatic evolution. Currently, little is known about the possible roles of tumor-derived EVs in sarcoma because the lack of specific surface… read more here.
Keywords: sarcoma; extracellular vesicles; chemistry; derived extracellular ... See more keywords
Patterns of care and outcome of CIC‐rearranged sarcoma patients: A nationwide study of the French sarcoma group
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DOI: 10.1002/cam4.5539
Abstract: CIC‐rearranged sarcomas (CIC‐RS) represent the most frequent subset of “Ewing‐like” undifferentiated small round cell sarcomas. These tumors tend to be more aggressive than Ewing sarcomas. Moreover, treatment strategy can differ according to teams. The primary… read more here.
Keywords: cic; sarcoma; care outcome; cic rearranged ... See more keywords
RNA sequencing of myeloid sarcoma, shed light on myeloid sarcoma stratification
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DOI: 10.1002/cam4.5654
Abstract: Myeloid sarcoma (MS) is a rare, extramedullary tumor consisting of myeloid blasts. Little is known about the genetic background of MS and the prognostic value of genetic abnormalities in MS. In particular, the broad variety… read more here.
Keywords: myeloid sarcoma; rna sequencing; sarcoma; sequencing myeloid ... See more keywords
Long‐term follow‐up results of pediatric and adolescent patients with localized Ewing sarcoma treated based on stratified modalities
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DOI: 10.1002/cam4.5703
Abstract: Compared with other pediatric tumors, little advances were achieved in studies on the stratified treatment in localized Ewing sarcoma. Most pediatric oncology groups treated Ewing sarcoma according to whether there was an existing metastasis, without… read more here.
Keywords: long term; sarcoma; ewing sarcoma; localized ewing ... See more keywords
Safety and efficacy of fruquintinib‐based therapy in patients with advanced or metastatic sarcoma
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DOI: 10.1002/cam4.7438
Abstract: The purpose of this study was to evaluate the efficacy and safety of fruquintinib‐based therapy as a salvage therapy for patients with advanced or metastatic sarcoma, including soft tissue sarcoma (STS) and bone sarcoma. read more here.
Keywords: therapy patients; therapy; sarcoma; based therapy ... See more keywords
Presentation and outcome of frequent and rare sarcoma histologic subtypes: A study of 10,262 patients with localized visceral/soft tissue sarcoma managed in reference centers
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DOI: 10.1002/cncr.31176
Abstract: The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. read more here.
Keywords: sarcoma; tissue sarcoma; soft tissue; presentation outcome ... See more keywords
A call to action: Why sarcoma surgery needs to be centralized
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DOI: 10.1002/cncr.31749
Abstract: In this issue, Keung et al present the results of their study using the National Cancer Data Base (NCDB) to compare the outcomes for patients undergoing surgery for primary retroperitoneal sarcoma (RPS) at low-volume hospitals… read more here.
Keywords: sarcoma; data sets; surgery; volume ... See more keywords
Three‐dimensional printing technology: A novel tool in guiding surgical management of retroperitoneal sarcoma
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DOI: 10.1002/cncr.35660
Abstract: Retroperitoneal sarcoma is a complex entity that requires specialized surgical management. Three‐dimensional printing technology may represent a valuable adjunctive tool for the preoperative assessment and surgical planning of retroperitoneal sarcoma. read more here.
Keywords: dimensional printing; printing technology; sarcoma; surgical management ... See more keywords
Fine‐needle aspiration biopsy of prostate synovial sarcoma: A case report and review of the literature
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DOI: 10.1002/dc.23623
Abstract: We describe a case of synovial sarcoma originating from prostate gland. The diagnosis was confirmed by fluorescent in situ hybridization analysis (FISH) for SYT rearrangement on the cell block. Synovial sarcoma is a high grade… read more here.
Keywords: sarcoma; needle aspiration; case; fine needle ... See more keywords
Role of fine needle aspiration cytology in the diagnosis of a rare case of a poorly differentiated synovial sarcoma with “Rhabdoid” features, including treatment implications
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DOI: 10.1002/dc.23712
Abstract: Synovial sarcoma is a high‐grade, soft tissue sarcoma that is relatively chemosensitive. Its exact diagnosis is crucial, including differentiation from its closest diagnostic mimic, ie, Ewing sarcoma, in view of different treatment options, including chemotherapy… read more here.
Keywords: sarcoma; poorly differentiated; diagnosis; rhabdoid features ... See more keywords
Biphasic axillary synovial sarcoma diagnosed by preoperative fine‐needle aspiration cytology
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DOI: 10.1002/dc.23750
Abstract: Synovial sarcoma (SS) is a soft‐tissue sarcoma which usually occurs in lower extremities. Less than 20 cases of SS located in shoulder or axillary region have been reported, and these studies describe histopathological features. We… read more here.
Keywords: sarcoma; aspiration cytology; needle aspiration; fine needle ... See more keywords