Abstract B61: Intratumoral oxygen gradients mediate sarcoma cell invasion
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DOI: 10.1158/1538-7445.epso16-b61
Abstract: Hypoxia is a critical factor in the progression and metastasis of many cancers including soft tissue sarcomas. Frequently, oxygen (O2) gradients develop in tumors as they grow beyond their vascular supply leading to heterogeneous areas… read more here.
Keywords: invasion; sarcoma cell; cell invasion; oxygen gradients ... See more keywords
Abstract B28: A cross-species enhancer activity analysis approach to identify the Ewing sarcoma cell of origin
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DOI: 10.1158/1538-7445.pedca19-b28
Abstract: Ewing sarcoma is a malignant bone and soft tissue tumor in children and adolescents. In 85% of all cases the formation of Ewing sarcoma is caused by a chromosomal translocation, leading to the expression of… read more here.
Keywords: cross species; sarcoma cell; cell origin; ewing sarcoma ... See more keywords
A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies
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DOI: 10.1186/s12885-018-4132-0
Abstract: BackgroundHistiocytic sarcoma is a rare disorder in humans, however it is seen with appreciable frequency in certain breeds of dogs, such as Bernese mountain dog. The purpose of this study was to fully characterize a… read more here.
Keywords: sarcoma cell; cell; cell line; histiocytic sarcoma ... See more keywords
Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells
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DOI: 10.18632/oncotarget.14291
Abstract: Soft tissue sarcomas with complex genomics are very heterogeneous tumors lacking simple prognosis markers or targeted therapies. Overexpression of a subset of mitotic genes from a signature called CINSARC is of bad prognosis, but the… read more here.
Keywords: cell lines; sarcoma cell; tetraploid; cell ... See more keywords
5-Aminolevrinic Acid Exhibits Dual Effects on Stemness in Human Sarcoma Cell Lines under Dark Conditions
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DOI: 10.3390/ijms24076189
Abstract: 5-aminolevulinic acid (ALA) is used for tumor-targeting phototherapy because it is converted to protoporphyrin IX (PPIX) upon excitation and induces phototoxicity. However, the effect of ALA on malignant cells under unexcited conditions is unclear. This… read more here.
Keywords: cell; ala; sphere forming; sarcoma cell ... See more keywords