Role of rat sarcoma virus mutations in cancer and potential target for cancer therapy
Sign Up to like & getrecommendations! Published in 2020 at "Future Science OA"
DOI: 10.2144/fsoa-2019-0045
Abstract: The prevalence of oncogenic rat sarcoma virus (RAS) mutations has made RAS a popular target for cancer therapies. Significant discoveries have been reported regarding cancer molecular biology following the study of RAS mutations. These discoveries… read more here.
Keywords: sarcoma virus; target cancer; cancer; rat sarcoma ... See more keywords
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Current cancer drug targets"
DOI: 10.2174/1568009623666230426093244
Abstract: The sarcoma virus oncogene (Src) tyrosine kinase, a nonreceptor protein-tyrosine kinase, plays a crucial role in cell survival, migration, differentiation and proliferation. The study of Src has developed considerably since it was first discovered as… read more here.
Keywords: sarcoma virus; related diseases; oncogene; virus oncogene ... See more keywords
Rous Sarcoma Virus RNA Stability Element Inhibits Deadenylation of mRNAs with Long 3′UTRs
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DOI: 10.3390/v9080204
Abstract: All retroviruses use their full-length primary transcript as the major mRNA for Group-specific antigen (Gag) capsid proteins. This results in a long 3′ untranslated region (UTR) downstream of the termination codon. In the case of… read more here.
Keywords: long utrs; rna stability; stability element; sarcoma virus ... See more keywords