Magnetic resonance imaging (MRI) helps differentiate renal cell carcinoma with sarcomatoid differentiation from renal cell carcinoma without sarcomatoid differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Abdominal Radiology"
DOI: 10.1007/s00261-022-03501-9
Abstract: The aim of the present study is to identify predictive imaging findings and construct a diagnostic model for differentiating renal cell carcinoma (RCC) with and without sarcomatoid dedifferentiation (sRCC and non-sRCC). This study is a… read more here.
Keywords: sarcomatoid differentiation; renal cell; tumor; cell carcinoma ... See more keywords
Pathologic and oncologic outcomes in patients with sarcomatoid differentiation undergoing cystectomy.
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DOI: 10.1111/bju.15428
Abstract: OBJECTIVE To evaluate whether urothelial carcinoma with sarcomatoid differentiation is associated with a lower pathologic response rate to neoadjuvant chemotherapy and worse oncologic outcomes compared to urothelial carcinoma without variant histology among patients undergoing radical… read more here.
Keywords: among patients; sarcomatoid differentiation; patients sarcomatoid; undergoing cystectomy ... See more keywords
Chromophobe Renal Cell Carcinoma with Sarcomatoid Differentiation: Clinicopathologic Correlation and Molecular Findings.
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DOI: 10.1177/10668969231167527
Abstract: Introduction: Sarcomatoid differentiation has been reported in approximately 8% of chromophobe renal cell carcinoma (RCC) and is associated with a worse prognosis. We aim to describe the clinicopathologic and molecular findings of chromophobe RCC with… read more here.
Keywords: renal cell; sarcomatoid differentiation; pathology; differentiation ... See more keywords
Significant response to nivolumab for metastatic chromophobe renal cell carcinoma with sarcomatoid differentiation: a case report
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DOI: 10.1186/s12894-018-0339-2
Abstract: BackgroundThe treatment of advanced or metastatic renal cell carcinoma (RCC) has drastically changed since the approval of immune checkpoint therapy. Nivolumab is a treatment option for patients with metastatic RCC, previously treated with targeted antiangiogenic… read more here.
Keywords: sarcomatoid differentiation; treatment; case; report ... See more keywords
Ki-67 index and percentage of sarcomatoid differentiation were two independent prognostic predictors in sarcomatoid renal cell carcinoma
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DOI: 10.2147/cmar.s176242
Abstract: Purpose To identify whether and which of pathological features of sarcomatoid differentiation (SD) in renal cell carcinoma (RCC) can be used as independent predictors associated with overall survival (OS). Materials and methods After institutional review… read more here.
Keywords: renal cell; index; cell carcinoma; sarcomatoid differentiation ... See more keywords
Genomic alteration of MTAP/CDKN2A predicts sarcomatoid differentiation and poor prognosis and modulates response to immune checkpoint blockade in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.953721
Abstract: Sarcomatoid differentiation is a highly aggressive pathological characteristic of renal cell carcinoma (RCC) and is characterized by susceptibility to progression and extremely poor prognosis. In this study, we included all genomic alteration events that led… read more here.
Keywords: mtap cdkn2a; rcc; cdkn2a mut; sarcomatoid differentiation ... See more keywords