First-line immune checkpoint inhibitors in advanced or metastatic renal cell carcinoma with sarcomatoid features.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2022.102374
Abstract: Advanced or metastasized renal cell carcinoma (mRCC) can present with sarcomatoid features, which is considered a poor prognosis marker and a treatment challenge. Several trials in first line mRCC have included immune checkpoint inhibitors (ICI)… read more here.
Keywords: renal cell; cell carcinoma; treatment; first line ... See more keywords
Combined MEK and PI3K/p110b inhibition as a novel targeted therapy for malignant mesothelioma displaying sarcomatoid features.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer research"
DOI: 10.1158/0008-5472.can-19-1633
Abstract: Among malignant mesotheliomas (MM) the sarcomatoid subtype is associated with higher chemoresistance and worst survival. Due to its low incidence, there has been little progress in the knowledge of the molecular mechanisms associated with sarcomatoid… read more here.
Keywords: pi3k; combined mek; targeted therapy; inhibition ... See more keywords
Abstract 6473: Outcomes of advanced renal cell carcinoma with sarcomatoid features post-cytoreductive nephrectomy in clear cell and non-clear cell disease
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinology"
DOI: 10.1158/1538-7445.am2020-6473
Abstract: Background: Cytoreductive nephrectomy in the setting of treatment of advanced renal cell carcinoma with sarcomatoid features (sRCC) has been highly contested in terms of added benefit for survival. Patients with sRCC are known to have… read more here.
Keywords: cytoreductive nephrectomy; cell; clear cell; sarcomatoid features ... See more keywords
High-dose interleukin 2 in patients with metastatic renal cell carcinoma with sarcomatoid features
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0190084
Abstract: Background High-dose interleukin-2 (HD IL-2) is used in the treatment of metastatic renal cell carcinoma (mRCC) and has an overall response rate (ORR) of 12–20% and a complete response rate (CR) of 8% in unselected… read more here.
Keywords: renal cell; cell carcinoma; mrcc sarcomatoid; patients mrcc ... See more keywords
Metastatic Renal Cell Carcinoma With Sarcomatoid Features.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology"
DOI: 10.46883/2022.25920955
Abstract: A previously healthy woman, aged 38 years, presented with a 3-month history of fatigue, dyspnea on exertion, significant weight loss, and severe left flank pain; her symptoms restricted any work activities. Laboratory test results were… read more here.
Keywords: cell; renal cell; sarcomatoid features; metastatic renal ... See more keywords