Abstract 416: Sarcomere Disassembly After Unloading is Regulated by Ubiquitination and Acetylation of Capz and α-actinin
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DOI: 10.1161/res.127.suppl_1.416
Abstract: Cardiac function mainly depends on the total myocyte mass in the ventricles. Assembly and disassembly of sarcomeres occurs to adjust this mass to altered mechanical demand. In the heart, hypertrophic cardiomyopathy results from myofibrillar assembly… read more here.
Keywords: disassembly unloading; omecamtiv mecarbil; acetylation; sarcomere disassembly ... See more keywords