Sargramostim in acute radiation syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2022.2143261
Abstract: ABSTRACT Introduction Since 1944, nearly 400 radiologic accidents/incidents have exposed about 3,000 people to substantial doses of ionizing radiation, with more than 125 deaths. Known are the Chernobyl and Fukushima nuclear power facility accidents, but… read more here.
Keywords: ionizing radiation; acute radiation; radiation syndrome; sargramostim ... See more keywords
Inhaled Sargramostim (Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor) for COVID-19-Associated Acute Hypoxemia: Results of the Phase 2, Randomized, Open-Label Trial (iLeukPulm).
Sign Up to like & getrecommendations! Published in 2022 at "Military medicine"
DOI: 10.1093/milmed/usac362
Abstract: INTRODUCTION Granulocyte-macrophage colony-stimulating factor (GM-CSF), a protein produced in the lung, is essential for pulmonary host defense and alveolar integrity. Prior studies suggest potential benefits in several pulmonary conditions, including acute respiratory distress syndrome and… read more here.
Keywords: inhaled sargramostim; sargramostim soc; covid associated; sargramostim ... See more keywords
Sargramostim and immune checkpoint inhibitors: combinatorial therapeutic studies in metastatic melanoma.
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DOI: 10.2217/imt-2021-0119
Abstract: The use of immune checkpoint inhibitors in patients with metastatic melanoma generates clinical benefit, including improved survival. Yet disease resistance and immune-related adverse events persist as unmet needs. Sargramostim, a yeast-derived recombinant human GM-CSF, has… read more here.
Keywords: immune checkpoint; sargramostim; metastatic melanoma; checkpoint inhibitors ... See more keywords