Excavating SARS‐coronavirus 2 genome for epitope‐based subunit vaccine synthesis using immunoinformatics approach
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29923
Abstract: Since the outbreak of severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) in December 2019 in China, there has been an upsurge in the number of deaths and infected individuals throughout the world, thereby leading to the… read more here.
Keywords: excavating sars; using immunoinformatics; immunoinformatics approach; sars coronavirus ... See more keywords
SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts
Sign Up to like & getrecommendations! Published in 2020 at "Virologica Sinica"
DOI: 10.1007/s12250-020-00242-1
Abstract: The ongoing outbreak of Coronavirus Disease 2019 (COVID-19) has become a global public health emergency. SARS-coronavirus-2 (SARS-CoV-2), the causative pathogen of COVID-19, is a positive-sense single-stranded RNA virus belonging to the family Coronaviridae . For… read more here.
Keywords: rna helicase; ntpase rna; sars coronavirus; sars cov ... See more keywords
SARS Coronavirus Redux
Sign Up to like & getrecommendations! Published in 2020 at "Trends in Immunology"
DOI: 10.1016/j.it.2020.02.007
Abstract: As an atypical pneumonia began to appear in December 2019, Zhou et al . worked with remarkable speed to identify the associated virus, determine its relationship to animal viruses, and evaluate factors conferring infection susceptibility… read more here.
Keywords: coronavirus redux; sars coronavirus;
SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling
Sign Up to like & getrecommendations! Published in 2017 at "Virus Research"
DOI: 10.1016/j.virusres.2017.04.008
Abstract: Abstract SARS coronavirus (CoV) papain-like protease (PLpro) reportedly induced the production of TGF-β1 through p38 MAPK/STAT3-meidated Egr-1-dependent activation (Sci. Rep. 6, 25754). This study investigated the correlation of PLpro-induced TGF-β1 with the expression of Type… read more here.
Keywords: type collagen; tgf; expression; sars coronavirus ... See more keywords
Contextualising SARS Coronavirus 2 and COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Microbiology Australia"
DOI: 10.1071/ma21002
Abstract: It is timely to assess where we are in the current SARS Coronavirus-2 pandemic. This edition of Microbiology Australia has national, and international, authorities authoring a series of papers on SARS Coronavirus 2 and related… read more here.
Keywords: microbiology; sars coronavirus; contextualising sars; coronavirus covid ... See more keywords
SARS-coronavirus-2 infections: biological instabilities characterized by order parameters
Sign Up to like & getrecommendations! Published in 2022 at "Physical Biology"
DOI: 10.1088/1478-3975/ac5155
Abstract: A four-variable virus dynamics TIIV model was considered that involves infected cells in an eclipse phase. The state space description of the model was transferred into an amplitude space description which is the appropriate general,… read more here.
Keywords: infected cells; sars coronavirus; order parameters; coronavirus infections ... See more keywords
Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvaa029
Abstract: Abstract Background A novel coronavirus of zoonotic origin (2019-nCoV) has recently been identified in patients with acute respiratory disease. This virus is genetically similar to SARS coronavirus and bat SARS-like coronaviruses. The outbreak was initially… read more here.
Keywords: 2019 ncov; sars coronavirus; novel coronavirus; ncov ... See more keywords
The reproductive number of COVID-19 is higher compared to SARS coronavirus
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Travel Medicine"
DOI: 10.1093/jtm/taaa021
Abstract: Teaser: Our review found the average R0 for 2019-nCoV to be 3.28, which exceeds WHO estimates of 1.4 to 2.5. read more here.
Keywords: covid higher; sars coronavirus; reproductive number; number covid ... See more keywords
Isothermal amplification using sequence-specific fluorescence detection of SARS coronavirus 2 and variants in nasal swabs
Sign Up to like & getrecommendations! Published in 2022 at "Biotechniques"
DOI: 10.2144/btn-2022-0037
Abstract: Coronavirus disease 2019 is a public health challenge requiring rapid testing for the detection of infections and transmission. Nucleic acid amplification tests targeting SARS coronavirus 2 (CoV2) are used to detect CoV2 in clinical samples.… read more here.
Keywords: sars coronavirus; amplification; detection; isothermal amplification ... See more keywords
Investigating Fungi-Derived Bioactive Molecules as Inhibitor of the SARS Coronavirus Papain Like Protease: Computational Based Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.752095
Abstract: Due to the rapid growth of the COVID-19 pandemic and its outcomes, developing a remedy to fight the predicament is critical. So far, it has infected more than 214,468,601 million people and caused the death… read more here.
Keywords: medicine; bioactive molecules; coronavirus papain; sars coronavirus ... See more keywords
pH-dependent endocytosis mechanisms for influenza A and SARS-coronavirus
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1190463
Abstract: The ongoing SARS-CoV-2 pandemic and the influenza epidemics have revived the interest in understanding how these highly contagious enveloped viruses respond to alterations in the physicochemical properties of their microenvironment. By understanding the mechanisms and… read more here.
Keywords: dependent endocytosis; endocytosis mechanisms; influenza sars; sars coronavirus ... See more keywords