Inactivated SARS-CoV-2 Vaccine Shows Cross-Protection against Bat SARS-Related Coronaviruses in Human ACE2 Transgenic Mice
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DOI: 10.1128/jvi.00169-22
Abstract: The genetic diversity of SARSr-CoVs in wildlife and their potential risk of cross-species infection highlight the necessity of developing wide-spectrum vaccines against infection of various SARSr-CoVs. In this study, we tested the protective efficacy of… read more here.
Keywords: protection; vaccine; sarsr covs; sars cov ... See more keywords
Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin
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DOI: 10.1128/mbio.03285-22
Abstract: Evaluation of the zoonotic risk of animal SARSr-CoVs is important for future disease preparedness. However, there are misconceptions regarding the risk of animal viruses. ABSTRACT In the last 2 decades, pathogens originating in animals may… read more here.
Keywords: sarsr covs; risk animal; sarsr; risk ... See more keywords
Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus
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DOI: 10.1371/journal.ppat.1006698
Abstract: A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in horseshoe bats since 2005 in different areas of China. However, these bat SARSr-CoVs show sequence differences from SARS coronavirus (SARS-CoV) in different genes (S,… read more here.
Keywords: sars cov; gene; sarsr covs; sars related ... See more keywords