SATB1 Expression Governs Epigenetic Repression of PD‐1 in Tumor‐Reactive T Cells
Sign Up to like & getrecommendations! Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2016.12.015
Abstract: &NA; Despite the importance of programmed cell death‐1 (PD‐1) in inhibiting T cell effector activity, the mechanisms regulating its expression remain poorly defined. We found that the chromatin organizer special AT‐rich sequence‐binding protein‐1 (Satb1) restrains… read more here.
Keywords: satb1 expression; repression; expression; cell ... See more keywords
Decreased SATB1 expression promotes AML cell proliferation through NF-κB activation
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cell International"
DOI: 10.1186/s12935-019-0850-x
Abstract: BackgroundSpecial AT-rich sequence-binding protein 1 (SATB1) is a chromatin-remodeling protein that regulates gene expressions in different types of cancer. Up-regulation of SATB1 is linked with progression of tumors. Our previous study showed that SATB1 expression… read more here.
Keywords: cell proliferation; expression; satb1 expression; satb1 ... See more keywords
Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202301897
Abstract: The genome organizer, special AT-rich binding protein-1 (SATB1) functions to globally regulate gene networks during primary T cells development and plays a pivotal role in lineage-specification in CD4+ helper-, CD8+ cytotoxic- and FOXP3+ regulatory-T cell… read more here.
Keywords: satb1 expression; th2 cells; enhancer essential; expression ... See more keywords
Transcriptional regulation of Satb1 in mouse trophoblast stem cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.918235
Abstract: SATB homeobox proteins are important regulators of developmental gene expression. Among the stem cell lineages that emerge during early embryonic development, trophoblast stem (TS) cells exhibit robust SATB expression. Both SATB1 and SATB2 act to… read more here.
Keywords: trophoblast stem; expression; satb1 expression; stem ... See more keywords