Human Myobundle Platform for Studying the Role of Notch Signaling in Satellite Cell Phenotype and Function
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202404695
Abstract: Notch signaling plays a pivotal role in regulating satellite cell (SC) behavior during skeletal muscle development, homeostasis, and repair. While well‐characterized in mouse models, the impact of Notch signaling in human muscle tissues remains largely… read more here.
Keywords: notch; satellite cell; muscle; function ... See more keywords
Low‐load resistance exercise during inactivity is associated with greater fibre area and satellite cell expression in older skeletal muscle
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12306
Abstract: Age‐related sarcopenia is accelerated by physical inactivity. Low‐load resistance exercise (LLRE) counters inactivity‐induced muscle atrophy in older adults, but changes in muscle fibre morphology are unstudied. We aimed to determine the impact of LLRE during… read more here.
Keywords: load resistance; muscle; low load; satellite cell ... See more keywords
Atrophic skeletal muscle fibre‐derived small extracellular vesicle miR‐690 inhibits satellite cell differentiation during ageing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13106
Abstract: Sarcopenia is a common and progressive skeletal muscle disorder characterized by atrophic muscle fibres and contractile dysfunction. Accumulating evidence shows that the number and function of satellite cells (SCs) decline and become impaired during ageing,… read more here.
Keywords: muscle; satellite cell; muscle fibres; atrophic skeletal ... See more keywords
Optimization of Satellite Cell Culture Through Biomaterials.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6771-1_18
Abstract: Hydrogels, a type of biomaterial, are an invaluable part of biomedical research as they are highly hydrated and properties such as elasticity, porosity, and ligand density can be tuned to desired values. Recently, culture substrate… read more here.
Keywords: muscle; cell culture; optimization satellite; satellite cell ... See more keywords
Early satellite cell communication creates a permissive environment for long-term muscle growth
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102372
Abstract: Summary Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking, satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show satellite cells communicate with other cells in skeletal muscle… read more here.
Keywords: communication; muscle; early satellite; satellite cell ... See more keywords
Satellite cell content and muscle regeneration in a mouse model of NAFLD.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition"
DOI: 10.1016/j.nut.2021.111570
Abstract: OBJECTIVES Muscle wasting is a common complication in patients with nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the effect of NAFLD on satellite cell (SC) content and skeletal muscle repair. METHODS Male… read more here.
Keywords: satellite cell; muscle; cell content; muscle regeneration ... See more keywords
Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2017.12.013
Abstract: Summary Satellite cells function as precursor cells in mature skeletal muscle homeostasis and regeneration. In healthy tissue, these cells are maintained in a state of quiescence by a microenvironment formed by myofibers and basement membrane… read more here.
Keywords: satellite; recapitulation extracellular; satellite cell; satellite cells ... See more keywords
Loss of MyoD and Myf5 in Skeletal Muscle Stem Cells Results in Altered Myogenic Programming and Failed Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2018.01.027
Abstract: Summary MyoD and Myf5 are fundamental regulators of skeletal muscle lineage determination in the embryo, and their expression is induced in satellite cells following muscle injury. MyoD and Myf5 are also expressed by satellite cell… read more here.
Keywords: skeletal muscle; myogenic programming; muscle; myod myf5 ... See more keywords
Nuclear entry of AS160 as a transcriptional regulator of satellite cells for muscle regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-64220-5
Abstract: Dysfunction of muscle satellite cells is linked to diabetic myopathy. The mechanisms vitiating muscle satellite cell proliferative activity in diabetes are not well understood. Here, we show that AS160, a key cytosolic Rab-GTPase activating protein… read more here.
Keywords: satellite; satellite cell; muscle; muscle regeneration ... See more keywords
Satellite cell proliferation and myofiber cross-section area increase after electrical stimulation following sciatic nerve crush injury in rats
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000000822
Abstract: Abstract Background Electrical stimulation has been recommended as an effective therapy to prevent muscle atrophy after nerve injury. However, the effect of electrical stimulation on the proliferation of satellite cells in denervated muscles has not… read more here.
Keywords: nerve; myofiber; satellite cell; electrical stimulation ... See more keywords
Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Physiology - Cell Physiology"
DOI: 10.1152/ajpcell.00429.2021
Abstract: The size of the satellite cell pool is reduced in estradiol (E2)-deficient female mice and humans. Here, we use a combination of in vivo and in vitro approaches to identify mechanisms, whereby E2 deficiency impairs… read more here.
Keywords: satellite cell; cell; cell pool; physiology ... See more keywords