Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis
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DOI: 10.1101/2022.04.04.486992
Abstract: Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by PCM1. To study the requirement for centriolar satellites, we generated mice lacking PCM1. Pcm1−/− mice display partially penetrant perinatal lethality with survivors exhibiting hydrocephalus,… read more here.
Keywords: ciliogenesis; centriolar satellites; mother centriole; expedite mother ... See more keywords