Articles with "saturation genome" as a keyword



SynDesign: web-based prime editing guide RNA design and evaluation tool for saturation genome editing

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Published in 2024 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkae304

Abstract: Abstract Saturation genome editing (SGE) enables in-depth functional evaluation of disease-associated genes and variants by generating all possible single nucleotide variants (SNVs) within a given coding region. Although prime editing can be employed for inducing… read more here.

Keywords: saturation genome; editing guide; prime editing; genome editing ... See more keywords