Topical treatments of Saussurea costus root and Thuja orientalis L. synergistically alleviate atopic dermatitis-like skin lesions by inhibiting protease-activated receptor-2 and NF-κB signaling in HaCaT cells and Nc/Nga mice.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.01.055
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The root of Saussurea costus (Aucklandia lappa Decne, Aucklandiae Radix, SC) and Thuja orientalis L. (TOL) have been traditionally used as anti-inflammatory agents in Korea. However, they have not been studied for the… read more here.
Keywords: hacat cells; tol; nga mice; dorsal skin ... See more keywords
Evaluation of Saussurea costus Nanoparticles in the Treatment of Periodontitis: Impact on NF-κB and TNF-α Expression
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DOI: 10.1055/s-0045-1810069
Abstract: Abstract Objectives Porphyromonas gingivalis is a major contributing pathogen in periodontitis and triggers an inflammatory response that leads to tissue damage, primarily through the activation of proinflammatory cytokines such as nuclear factor kappa B (NF-κB)… read more here.
Keywords: costus; periodontitis; saussurea costus; costus nanoparticles ... See more keywords
Synergistic hepatoprotection by supplementing Saussurea costus (falc.) lipsch and Glycyrrhiza glabra L. in combination against Diethylnitrosamine-induced liver damage in rats.
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DOI: 10.1080/01480545.2025.2564431
Abstract: This study aims to evaluate the hepatoprotective effects of combined Saussurea costus and Glycyrrhiza glabra extracts against diethylnitrosamine (DEN)-induced hepatic damage in rats. In the present investigation, the in vivo experimental study involved forty-two male… read more here.
Keywords: saussurea costus; damage; liver damage; glycyrrhiza glabra ... See more keywords
Chemical and biological evaluation of essential oil from Saussurea costus (Falc.) Lipsch. from Garhwal Himalaya collected at different harvesting periods
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DOI: 10.1080/14786419.2018.1440219
Abstract: Abstract The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year… read more here.
Keywords: costus falc; saussurea costus; falc lipsch;
Clinical significance of Saussurea Costus in thyroid treatment
Sign Up to like & getrecommendations! Published in 2020 at "Saudi Medical Journal"
DOI: 10.15537/smj.2020.10.25416
Abstract: Saussurea costus (S. costus) belongs to family of Asteraceae and is one of the therapeutic plants extensively used as a traditional medicine in Saudi Arabia. Constituents of this plant have the potential to be developed… read more here.
Keywords: costus; costus thyroid; thyroid treatment; saussurea costus ... See more keywords
Exploring the Antifungal Activity and Action of Saussurea costus Root Extracts against Candida albicans and Non-albicans Species
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DOI: 10.3390/antibiotics11030327
Abstract: The isolation and assessment of the active constituents in polar and non-polar crude extracts of Saussurea costus roots as antifungal agents, against Candida albicans and non-C. albicans (NAC) species, was the aim of this current… read more here.
Keywords: albicans non; saussurea costus; activity; non albicans ... See more keywords
Protective Potential of Saussurea costus (Falc.) Lipsch. Roots against Cyclophosphamide-Induced Pulmonary Injury in Rats and Its In Vitro Antiviral Effect
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DOI: 10.3390/ph16020318
Abstract: Diseases and infections of the respiratory tract are common global causes of morbidity and mortality. Our study attempts to elucidate a novel remedy for respiratory ailments, in addition to identifying and quantifying the metabolites of… read more here.
Keywords: protective potential; cyclophosphamide induced; saussurea costus; vitro antiviral ... See more keywords