Structural Characterization of N-WASP Domain V Using MD Simulations with NMR and SAXS Data.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.02.015
Abstract: Because of their large conformational heterogeneity, structural characterization of intrinsically disordered proteins (IDPs) is very challenging using classical experimental methods alone. In this study, we use NMR and small-angle x-ray scattering (SAXS) data with multiple… read more here.
Keywords: nmr saxs; saxs data; characterization wasp; structural characterization ... See more keywords
Bayesian refinement of protein structures and ensembles against SAXS data using molecular dynamics
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005800
Abstract: Small-angle X-ray scattering is an increasingly popular technique used to detect protein structures and ensembles in solution. However, the refinement of structures and ensembles against SAXS data is often ambiguous due to the low information… read more here.
Keywords: protein structures; molecular dynamics; structures ensembles; ensembles saxs ... See more keywords
Automatic Bayesian Weighting for SAXS Data
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.671011
Abstract: Small-angle X-ray scattering (SAXS) experiments are important in structural biology because they are solution methods, and do not require crystallization of protein complexes. Structure determination from SAXS data, however, poses some difficulties. Computation of a… read more here.
Keywords: saxs; automatic bayesian; biology; saxs data ... See more keywords