Articles with "sbcma" as a keyword



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Soluble TACI and soluble BCMA as biomarkers in primary central nervous system lymphoma

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Published in 2017 at "Neuro-Oncology"

DOI: 10.1093/neuonc/nox097

Abstract: Background B-cell survival is regulated through interactions of B-cell-activating factor and a proliferation-inducing ligand with their receptors transmembrane activator and CAML interactor (TACI) and B-cell maturation antigen (BCMA). We evaluated the diagnostic potential of soluble… read more here.

Keywords: soluble bcma; soluble taci; bcma; sbcma ... See more keywords
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Baseline and Increases in Serum B-Cell Maturation Antigen Levels Rapidly Indicate Changes in Clinical Status Among Relapsed/Refractory Multiple Myeloma Patients Undergoing New Treatments

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Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-132012

Abstract: Introduction: B-cell maturation antigen (BCMA) is a protein that is expressed on malignant plasma cells from patients (pts) with multiple myeloma (MM). Our group has previously shown that MM pts have higher levels of serum… read more here.

Keywords: protein; pfs; sbcma; cycle ... See more keywords
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Effects of teclistamab and talquetamab on soluble BCMA levels in patients with relapsed/refractory multiple myeloma

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Published in 2022 at "Blood Advances"

DOI: 10.1182/bloodadvances.2022007625

Abstract: B-cell maturation antigen (BCMA) is selectively expressed as a surface protein on plasma cells and is a validated target for multiple myeloma (MM). A soluble form of BCMA (sBCMA) is elevated in the sera of… read more here.

Keywords: sbcma levels; sbcma; bcma; talquetamab ... See more keywords

Teclistamab and talquetamab modulate levels of soluble B-cell maturation antigen in patients with relapsed and/or refractory multiple myeloma.

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Published in 2021 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2021.39.15_suppl.8047

Abstract: 8047 Background: B-cell maturation antigen (BCMA, CD269) is a single transmembrane protein that is selectively expressed in the B-cell lineage and is a validated target for multiple myeloma. BCMA exists as both surface protein and… read more here.

Keywords: sbcma; teclistamab; teclistamab talquetamab; multiple myeloma ... See more keywords