1,5-Benzoxazepines as a unique and potent scaffold for activity drugs: A review.
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100224
Abstract: Benzoxazepines constitute a huge number of organic compounds widely described in the literature. Many of them are distinguished by their biological properties. Among them, our attention was drawn to 1,5-benzoxazepine derivatives due to their interesting… read more here.
Keywords: scaffold activity; drugs review; activity drugs; potent scaffold ... See more keywords
Flotillin scaffold activity contributes to type VII secretion system assembly in Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006728
Abstract: Scaffold proteins are ubiquitous chaperones that promote efficient interactions between partners of multi-enzymatic protein complexes; although they are well studied in eukaryotes, their role in prokaryotic systems is poorly understood. Bacterial membranes have functional membrane… read more here.
Keywords: vii secretion; staphylococcus aureus; scaffold activity; type vii ... See more keywords