Exploiting the Thiobarbituric Acid Scaffold for Antibacterial Activity
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DOI: 10.1002/cmdc.201800414
Abstract: Thiobarbituric acid (TBA) has been considered a privileged structure for developing antimicrobial agents. Diversity was obtained at positions N and at C5 through acylation, Schiff base formation, Knoevenagel condensation, and thioamide and enamine formation. The… read more here.
Keywords: acid; thiobarbituric acid; acid scaffold; scaffold antibacterial ... See more keywords
An nMgO containing scaffold: Antibacterial activity, degradation properties and cell responses
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DOI: 10.18063/ijb.v4i1.120
Abstract: Bone repair failure caused by implant-related infections is a common and troublesome problem. In this study, an antibacterial scaffold was developed via selective laser sintering with incorporating nano magnesium oxide (nMgO) to poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). The… read more here.
Keywords: degradation; containing scaffold; antibacterial activity; nmgo containing ... See more keywords
Impact of Indazole scaffold as Antibacterial and Antifungal agent.
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DOI: 10.2174/1568026622666220512145646
Abstract: Heterocycles consisting of nitrogen atom, Indazole, is a pungent, biological, heterocyclic, bicyclic compounds possessing electron rich portions. Indazole composed of two nitrogen atoms put under the azoles family, further called as isoindazolone. It is a… read more here.
Keywords: impact indazole; antifungal agent; scaffold antibacterial; antibacterial antifungal ... See more keywords
Quinones as an Efficient Molecular Scaffold in the Antibacterial/Antifungal or Antitumoral Arsenal
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DOI: 10.3390/ijms232214108
Abstract: Quinone-based compounds constitute several general classes of antibiotics that have long shown unwavering efficiency against both Gram-positive and Gram-negative microbial infections. These quinone-based antibiotics are increasingly popular due to their natural origins and are used… read more here.
Keywords: efficient molecular; molecular scaffold; scaffold antibacterial; quinone based ... See more keywords