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   Articles with "scaffold based" as a keyword



In vitro remodeling and structural characterization of degradable polymer scaffold-based tissue-engineered vascular grafts using optical coherence tomography

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recommendations! Published in 2017 at "Cell and Tissue Research"

DOI: 10.1007/s00441-017-2683-z

Abstract: Non-destructive imaging strategies to monitor long-term cultures is essential for vascular engineering. The goal of this study is to investigate whether optical coherence tomography (OCT) can be a suitable approach to monitor the long-term remodeling… read more here.

Keywords: optical coherence; based tissue; microscopy; scaffold based ... See more keywords

Bioresorbable Scaffold-Based Controlled Drug Delivery for Restenosis

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recommendations! Published in 2018 at "Journal of Cardiovascular Translational Research"

DOI: 10.1007/s12265-018-9841-x

Abstract: Bioresorbable scaffolds have emerged as a potential alternative to non-erodible metal implants to alleviate the long-term risk of permanent device vascular implant-related adverse events. Bioresorbable scaffolds provide a temporary mechanical support function until the vessel… read more here.

Keywords: scaffold based; drug; based controlled; bioresorbable scaffold ... See more keywords
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Benzimidazole scaffold based hybrid molecules for various inflammatory targets: Synthesis and evaluation.

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recommendations! Published in 2018 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2018.05.014

Abstract: Designing of hybrid drugs with specific multitarget profile is a promising line of attack against inflammation. In light of this, a series of benzimidazole scaffold based hybrid molecules were designed by integrating benzimidazoles (containing pharmacophoric… read more here.

Keywords: hybrid molecules; scaffold based; benzimidazole scaffold; lox ... See more keywords
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1-Isoindolinone scaffold-based natural products with a promising diverse bioactivity.

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recommendations! Published in 2020 at "Fitoterapia"

DOI: 10.1016/j.fitote.2020.104722

Abstract: Isoindolin-1-one or 1-isoindolinone framework is referred to phthalimidines or benzo fused γ-lactams of the corresponding γ-amino carboxylic acids and has been of prime interest for scientists for last several decades. 1-Isoindolinone framework is found in… read more here.

Keywords: isoindolinone scaffold; natural products; scaffold based; chemistry ... See more keywords
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The Synergy of Scaffold-Based and Scaffold-Free Tissue Engineering Strategies.

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recommendations! Published in 2018 at "Trends in biotechnology"

DOI: 10.1016/j.tibtech.2018.01.005

Abstract: Tissue engineering (TE) is a highly interdisciplinary research field driven by the goal to restore, replace, or regenerate defective tissues. Throughout more than two decades of intense research, different technological approaches, which can be principally… read more here.

Keywords: based scaffold; scaffold free; scaffold based; tissue engineering ... See more keywords

High-throughput Phosphotyrosine Protein Complexes Screening by Photoaffinity-engineered Protein Scaffold-based Forward-phase Protein Array.

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recommendations! Published in 2019 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.9b01845

Abstract: Low abundance phosphotyrosine (pTyr)-mediated signaling protein complexes play critical roles in cancer signaling. The precise and comprehensive profiling of these pTyr-mediated protein complexes remains challenging due to their dynamic nature and weak binding affinity. Taking… read more here.

Keywords: protein; scaffold based; ptyr; based forward ... See more keywords

Synthesis of Farnesyloxy- and Drimanyloxy-Arene Scaffold-Based Hybrid Molecules as Antifungals against Botrytis cinerea

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recommendations! Published in 2025 at "Journal of Agricultural and Food Chemistry"

DOI: 10.1021/acs.jafc.5c06584

Abstract: There is an increasing interest in the use of biopesticides, which implies the use of living microorganisms, plant and microbial extracts, and natural products isolated from the above-mentioned sources or closely related derivatives. In this… read more here.

Keywords: farnesyloxy drimanyloxy; synthesis farnesyloxy; arene scaffold; drimanyloxy arene ... See more keywords

Carbenoid-involved reactions integrated with scaffold-based screening generates a Nav1.7 inhibitor

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recommendations! Published in 2024 at "Communications Chemistry"

DOI: 10.1038/s42004-024-01213-3

Abstract: Voltage-gated sodium channel subtype Nav1.7 is a promising drug target associated with neuropathic pain disorder, however, the current Nav1.7 inhibitors show limited efficacy in clinical trials. More new molecular entities need to be discovered. Here,… read more here.

Keywords: screening; carbenoid involved; nav1 inhibitor; inhibitor ... See more keywords
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Utilizing an Old Idea for the Three-Component Synthesis of Anthraquinone-Scaffold-Based Enaminodiones (2,2-Diacylethenamines)

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recommendations! Published in 2020 at "Polycyclic Aromatic Compounds"

DOI: 10.1080/10406638.2020.1747096

Abstract: An efficient, novel, and direct approach synthetic protocol for the construction of anthraquinone scaffold-based aminomethylene cycloalkane-1,3-diones (enaminodiones) is described. The developed on... read more here.

Keywords: idea three; anthraquinone scaffold; utilizing old; scaffold based ... See more keywords

Scaffold-Based Tissue Engineering Strategies for Osteochondral Repair

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recommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2021.812383

Abstract: Over centuries, several advances have been made in osteochondral (OC) tissue engineering to regenerate more biomimetic tissue. As an essential component of tissue engineering, scaffolds provide structural and functional support for cell growth and differentiation.… read more here.

Keywords: scaffold based; engineering strategies; based tissue; tissue engineering ... See more keywords

Technological Advances of 3D Scaffold-Based Stem Cell/Exosome Therapy in Tissues and Organs

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recommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.709204

Abstract: Recently, biomaterial scaffolds have been widely applied in the field of tissue engineering and regenerative medicine. Due to different production methods, unique types of three-dimensional (3D) scaffolds can be fabricated to meet the structural characteristics… read more here.

Keywords: scaffold based; exosome therapy; stem cell; tissues organs ... See more keywords