Coculture of Spheroids/2D Cell Layers Using a Miniaturized Patterned Platform as a Versatile Method to Produce Scaffold‐Free Tissue Engineering Building Blocks
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700069
Abstract: A hanging drop system that allows the multiconfigurational coculture of 3D microtissues is suggested as a versatile platform to promote the formation of functional preconditioned spheroids/microtissues, namely stem‐cell‐derived tissue engineering microtissues, with potential to be… read more here.
Keywords: building blocks; scaffold free; platform; coculture ... See more keywords
Scaffold‐free tissue engineering of functional corneal stromal tissue
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2363
Abstract: Blinding corneal scarring is predominately treated with allogeneic graft tissue; however, there is a worldwide shortage of donor tissue leaving millions in need of therapy. Human corneal stromal stem cells (CSSC) have been shown produce… read more here.
Keywords: corneal; scaffold free; corneal stromal; tissue ... See more keywords
Modelling glioma invasion using 3D bioprinting and scaffold-free 3D culture
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-018-0469-z
Abstract: Glioma is a highly aggressive form of brain cancer, with some subtypes having 5-year survival rates of less than 5%. Tumour cell invasion into the surrounding parenchyma seems to be the primary driver of these… read more here.
Keywords: glioma; microscopy; invasion; scaffold free ... See more keywords
An allogenic 3D scaffold-free tissue engineered product for deep thickness skin regeneration: in vitro development to in vivo proof of concept
Sign Up to like & getrecommendations! Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.03.018
Abstract: Background & Aim Deep thickness skin wound remains a major challenge for reconstructive surgery. A novel approach of tissue engineering, based on an allogeneic adipose-derived 3D scaffold-free technology, was proposed. Methods, Results & Conclusion Material… read more here.
Keywords: thickness skin; scaffold free; graft; tissue ... See more keywords
Histological evaluation of tendon formation using a scaffold-free three-dimensional-bioprinted construct of human dermal fibroblasts under in vitro static tensile culture
Sign Up to like & getrecommendations! Published in 2019 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2019.02.002
Abstract: Introduction Tendon tissue engineering requires scaffold-free techniques for safe and long-term clinical applications and to explore alternative cell sources to tenocytes. Therefore, we histologically assessed tendon formation in a scaffold-free Bio-three-dimensional (3D) construct developed from… read more here.
Keywords: scaffold free; group; tendon; tensile culture ... See more keywords
The Synergy of Scaffold-Based and Scaffold-Free Tissue Engineering Strategies.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2018.01.005
Abstract: Tissue engineering (TE) is a highly interdisciplinary research field driven by the goal to restore, replace, or regenerate defective tissues. Throughout more than two decades of intense research, different technological approaches, which can be principally… read more here.
Keywords: based scaffold; scaffold free; scaffold based; tissue engineering ... See more keywords
Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-19024-z
Abstract: Adipose tissue dysfunction is critical to the development of type II diabetes and other metabolic diseases. While monolayer cell culture has been useful for studying fat biology, 2D culture often does not reflect the complexity… read more here.
Keywords: adipose spheroids; scaffold free; tissue; biology ... See more keywords
The Self-Assembling Process and Applications in Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a025668
Abstract: Tissue engineering strives to create neotissues capable of restoring function. Scaffold-free technologies have emerged that can recapitulate native tissue function without the use of an exogenous scaffold. This review will survey, in particular, the self-assembling… read more here.
Keywords: scaffold free; self assembling; tissue engineering; tissue ... See more keywords
The Efficacy of a Scaffold-free Bio 3D Conduit Developed from Autologous Dermal Fibroblasts on Peripheral Nerve Regeneration in a Canine Ulnar Nerve Injury Model: A Preclinical Proof-of-Concept Study
Sign Up to like & getrecommendations! Published in 2019 at "Cell Transplantation"
DOI: 10.1177/0963689719855346
Abstract: Autologous nerve grafting is widely accepted as the gold standard treatment for segmental nerve defects. To overcome the inevitable disadvantages of the original method, alternative methods such as the tubulization technique have been developed. Several… read more here.
Keywords: bio conduit; scaffold free; nerve; dermal fibroblasts ... See more keywords
The efficacy of a scaffold-free Bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171448
Abstract: Background Although autologous nerve grafting is the gold standard treatment of peripheral nerve injuries, several alternative methods have been developed, including nerve conduits that use supportive cells. However, the seeding efficacy and viability of supportive… read more here.
Keywords: scaffold free; group; nerve; sciatic nerve ... See more keywords
Dental Pulp Stem Cell-Derived, Scaffold-Free Constructs for Bone Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19071846
Abstract: In the present study, a scaffold-free tissue construct was developed as an approach for the regeneration of tissue defects, which produced good outcomes. We fabricated a scaffold-free tissue construct from human dental pulp stem cells… read more here.
Keywords: osteogenic induction; scaffold free; regeneration; hdpsc constructs ... See more keywords