Novel biotechnology approaches in colorectal cancer diagnosis and therapy
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2303-8
Abstract: With ever-increasing molecular information about colorectal cancer (CRC), there is an expectation to detect more sensitive and specific molecular markers for new advanced diagnostic methods that can surpass the limitations of current screening tests. Moreover,… read more here.
Keywords: therapy; biotechnology; diagnosis; colorectal cancer ... See more keywords
Reciprocal stabilisation of glycine receptors and gephyrin scaffold proteins at inhibitory synapses.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.01.024
Abstract: Postsynaptic scaffold proteins immobilise neurotransmitter receptors in the synaptic membrane opposite to presynaptic vesicle release sites, thus ensuring efficient synaptic transmission. At inhibitory synapses in the spinal cord, the main scaffold protein gephyrin assembles in… read more here.
Keywords: inhibitory synapses; scaffold proteins; glycine receptors; gephyrin ... See more keywords
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.add7969
Abstract: RAS-ERK (extracellular signal–regulated kinase) pathway signals are modulated by scaffold proteins that assemble the components of different kinase tiers into a sequential phosphorylation cascade. In the prevailing model scaffold proteins function as isolated entities, where… read more here.
Keywords: trans phosphorylation; scaffold protein; scaffold proteins; kinase ... See more keywords
Small GTPase Cdc42, WASP, and scaffold proteins for higher-order assembly of the F-BAR domain protein
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adf5143
Abstract: The higher-order assembly of Bin-amphiphysin-Rvs (BAR) domain proteins, including the FCH-BAR (F-BAR) domain proteins, into lattice on the membrane is essential for the formation of subcellular structures. However, the regulation of their ordered assembly has… read more here.
Keywords: scaffold proteins; order assembly; higher order; bar domain ... See more keywords
Advances in Plant-Derived Scaffold Proteins
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00122
Abstract: Scaffold proteins form critical biomatrices that support cell adhesion and proliferation for regenerative medicine and drug screening. The increasing demand for such applications urges solutions for cost effective and sustainable supplies of hypoallergenic and biocompatible… read more here.
Keywords: advances plant; plant; plant derived; drug ... See more keywords