Aromatic interactions in β-hairpin scaffold stability: A historical perspective.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.11.001
Abstract: Non-covalent interactions between naturally occurring aromatic residues have been widely exploited as scaffold stabilizing agents in de novo designed peptides and in Nature - inspired structures. Our understanding of the factors driving aromatic interactions and… read more here.
Keywords: historical perspective; interactions hairpin; scaffold stability; stability historical ... See more keywords
Progressive Ataxia, Memory Impairments, and Seizure Episodes in Spna2 R1098Q Mouse Variant Affecting Alpha II Spectrin’s Scaffold Stability
Sign Up to like & getrecommendations! Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13020261
Abstract: SPTAN1 spectrinopathies refer to a group of rare, inherited diseases associated with damage to non-erythrocytic α-II spectrin (α-II). They are linked to a range of mild to severe neuropathologies of the central and peripheral nervous… read more here.
Keywords: spectrin; scaffold stability; progressive ataxia; memory ... See more keywords