Four and a half domain 2 (FHL2) scaffolding protein is a marker of connective tissues of developing digits and regulates fibrogenic differentiation of limb mesodermal progenitors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2637
Abstract: Four and a half LIM domain 2 (FHL2) is a multifunctional scaffolding protein of well‐known function regulating cell signalling cascades and gene transcription in cancer tissues. However, its function in embryonic systems is poorly characterized.… read more here.
Keywords: four half; scaffolding protein; domain fhl2; connective tissues ... See more keywords
Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.08.2922
Abstract: Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised… read more here.
Keywords: version; dysregulates phosphodiesterase; disc1 dysregulates; scaffolding protein ... See more keywords
The Requirement for GW182 Scaffolding Protein Depends on Whether Argonaute Is Mediating Translation, Transcription, or Splicing.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00602
Abstract: GW182 and argonaute 2 (AGO2) are core proteins of the RNA interference complex. GW182 is a scaffolding protein that physically associates with AGO2 and bridges its interactions with other proteins. A fundamental problem in biology… read more here.
Keywords: protein; gw182; requirement gw182; protein depends ... See more keywords
A viral scaffolding protein triggers portal ring oligomerization and incorporation during procapsid assembly
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DOI: 10.1126/sciadv.1700423
Abstract: A novel role for scaffolding protein in portal ring formation. Most double-stranded DNA viruses package genetic material into empty precursor capsids (or procapsids) through a dodecameric portal protein complex that occupies 1 of the 12… read more here.
Keywords: protein; scaffolding protein; viral scaffolding; portal ring ... See more keywords
Hexameric rings of the scaffolding protein CheW enhance response sensitivity and cooperativity in Escherichia coli chemoreceptor arrays
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abj1737
Abstract: The Escherichia coli chemoreceptor array is a supramolecular assembly that enables cells to respond to extracellular cues dynamically and with great precision and sensitivity. In the array, transmembrane receptors organized as trimers of dimers are… read more here.
Keywords: sensitivity; chew; protein chew; scaffolding protein ... See more keywords
Cryo-EM Structure of Gokushovirus ΦEC6098 Reveals a Novel Capsid Architecture for a Single-Scaffolding Protein, Microvirus Assembly System
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00990-22
Abstract: There is a dramatic structural and morphogenetic divide within the Microviridae. The well-studied ΦX174-like viruses have prominent spikes at their icosahedral vertices, which are absent in gokushoviruses. ABSTRACT Ubiquitous and abundant in ecosystems and microbiomes,… read more here.
Keywords: structure; scaffolding protein; ec6098; capsid ... See more keywords
Coat Protein Mutations That Alter the Flux of Morphogenetic Intermediates through the ϕX174 Early Assembly Pathway
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DOI: 10.1128/jvi.01384-17
Abstract: ABSTRACT Two scaffolding proteins orchestrate ϕX174 morphogenesis. The internal scaffolding protein B mediates the formation of pentameric assembly intermediates, whereas the external scaffolding protein D organizes 12 of these intermediates into procapsids. Aromatic amino acid… read more here.
Keywords: protein; scaffolding protein; coat protein; assembly ... See more keywords
Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.
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DOI: 10.1261/rna.078709.121
Abstract: TNRC6 is a scaffolding protein that bridges interactions between small RNAs, argonaute (AGO) protein, and effector proteins to control gene expression. There are three paralogs in mammalian cells, TNRC6A, TNRC6B, and TNRC6C. These paralogs have… read more here.
Keywords: tnrc6 paralogs; gene; scaffolding protein; gene expression ... See more keywords
Expression of the Excitatory Postsynaptic Scaffolding Protein, Shank3, in Human Brain: Effect of Age and Alzheimer’s Disease
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DOI: 10.3389/fnagi.2021.717263
Abstract: Shank3 is a postsynaptic scaffolding protein of excitatory synapses. Mutations or variations of SHANK3 are associated with various psychiatric and neurological disorders. We set to determine its normal expression pattern in the human brain, and… read more here.
Keywords: excitatory; scaffolding protein; postsynaptic scaffolding; expression ... See more keywords