Insights into the regulation of mRNA translation by scaffolding proteins
Sign Up to like & getrecommendations! Published in 2024 at "Biochemical Society Transactions"
DOI: 10.1042/bst20241021
Abstract: Regionalisation of molecular mechanisms allows cells to fine-tune their responses to dynamic environments. In this context, scaffolds are well-known mediators of localised protein activity. These phenomenal proteins act as docking sites where pathway components are… read more here.
Keywords: translation scaffolding; mrna translation; scaffolding proteins; regulation mrna ... See more keywords
HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53.
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-oncology"
DOI: 10.1093/neuonc/noz215
Abstract: BACKGROUND Diffuse midline glioma (DMG) is a pediatric malignancy with poor prognosis. Most children die less than one year after diagnosis. Recently, mutations in histone H3 have been identified and are believed to be oncogenic… read more here.
Keywords: glioma; dmg; treatment; ebp50 irsp53 ... See more keywords