1,2,4- and 1,3,4-Oxadiazoles as Scaffolds in the Development of Antiparasitic Agents
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DOI: 10.21577/0103-5053.20170208
Abstract: In this review, we present the potential use of the heterocyclic oxadiazole rings in the design and synthesis of new drugs to treat parasitic infections. We intend to compare herein all the four isomeric forms… read more here.
Keywords: antiparasitic agents; scaffolds development; oxadiazoles scaffolds; development antiparasitic ... See more keywords
Multicyclic Peptides as Scaffolds for the Development of Tumor Targeting Agents.
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DOI: 10.2174/0929867324666170316120304
Abstract: The lack of specificity of traditional cytotoxic drugs triggers the development of anticancer agents with high selectivity to tumor-specific proteins. The unveiling of target structures such as EGFR or Her2 allows the focused development of… read more here.
Keywords: scaffolds development; multicyclic peptides; development; display techniques ... See more keywords