Peptidic Scaffolds To Reduce the Interaction of Cu(II) Ions with β-Amyloid Protein.
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DOI: 10.1021/acs.inorgchem.9b03099
Abstract: Competitive Cu(II)-binding studies have been carried out between five decapeptides (both acyclic and cyclic), namely C-Asp, C-Asn, O-Asp, ODPro-Asp, and O-Asn, and the Aβ(1-16) and Aβ(1-40) fragments. Conformational constraints in such peptidic scaffolds affect their… read more here.
Keywords: protein; scaffolds reduce; interaction ions; interaction ... See more keywords