LAUSR

Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion

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1 Published in 2017 at "PLoS Computational Biology"

DOI: 10.1371/journal.pcbi.1005341

Abstract: CRISPR-Cas9 technology can be used to engineer precise genomic deletions with pairs of single guide RNAs (sgRNAs). This approach has been widely adopted for diverse applications, from disease modelling of individual loci, to parallelized loss-of-function… read more here.

Keywords: guide rnas; genomic deletion; scalable design; deletion ... See more keywords