Systematic study of paracetamol powder mixtures and granules tabletability: key role of rheological properties and dynamic image analysis.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121110
Abstract: The aim of this systematic study was to analyze the granulometric and rheological behavior of tableting mixtures in relation to tabletability by single tablet and lab-scale batch compression with an eccentric tablet machine. Three mixtures… read more here.
Keywords: compression; tabletability; powder; lab scale ... See more keywords
Integrating QbD tools for flexible scale up batch size selection for solid dosage forms.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2019.12.007
Abstract: The pilot scale batch size for solid oral dosage forms is currently defined by major regulatory agencies as one-tenth of the full production, or 100,000 units, whichever is larger. The current criteria is arbitrary and… read more here.
Keywords: selection; batch size; size; dosage forms ... See more keywords