Interactions Between Large-Scale Functional Brain Networks are Captured by Sparse Coupled HMMs
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Medical Imaging"
DOI: 10.1109/tmi.2017.2755369
Abstract: Functional magnetic resonance imaging (fMRI) provides a window on the human brain at work. Spontaneous brain activity measured during resting-state has already provided many insights into brain function. In particular, recent interest in dynamic interactions… read more here.
Keywords: large scale; scale functional; network; sparse coupled ... See more keywords
Abstract SY14-02: Mapping synthetic lethal interactions at scale: A functional genomics approach to cancer therapeutic discovery
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-sy14-02
Abstract: The Cancer Dependency Map (DepMap) is an ongoing initiative to identify and explore synthetic lethal targets, by systematically linking tumor molecular alterations to gene dependencies and drug sensitivities. The resource used by scientists worldwide has… read more here.
Keywords: cancer; mapping synthetic; interactions scale; scale functional ... See more keywords
Structural instability of large-scale functional networks
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0181247
Abstract: We study how large functional networks can grow stably under possible cascading overload failures and evaluated the maximum stable network size above which even a small-scale failure would cause a fatal breakdown of the network.… read more here.
Keywords: large scale; structural instability; scale functional; network ... See more keywords
Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10123148
Abstract: Major progress has been made over the last decade in identifying novel genes involved in neurodevelopmental disorders, although the task of elucidating their corresponding molecular and pathophysiological mechanisms, which are an essential prerequisite for developing… read more here.
Keywords: intellectual disabilities; large scale; scale functional; genes involved ... See more keywords
How Does the Scale and Functional Diversity of the Innovation Cooperation Network Affect Local Innovation? Township-Level Evidence from Beijing
Sign Up to like & getrecommendations! Published in 2025 at "Land"
DOI: 10.3390/land14051115
Abstract: The innovation cooperation network (ICN) drives innovation. However, how its network diversity affects local innovation needs further exploration. This paper examines the effects of ICN’s scale and functional diversity on local innovation. Employing the township-level… read more here.
Keywords: innovation; local innovation; functional diversity; network ... See more keywords
Mesoscopic-scale functional networks in the primate amygdala
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.57341
Abstract: The primate amygdala performs multiple functions that may be related to the anatomical heterogeneity of its nuclei. Individual neurons with stimulus- and task-specific responses are not clustered in any of the nuclei, suggesting that single-units… read more here.
Keywords: scale functional; primate amygdala; mesoscopic scale; functional networks ... See more keywords